Client

Job Summary:

The Client-Based Researcher I position will work with the faculty leader, Dr. Josh Lang, in the fields of Human Molecular Biology and Cellular Immunology at the UW Carbone Cancer Center (UWCCC), as a member of the Circulating Biomarker Core (CBC). The focus of the CBC is to provide sample processing and analysis services to members of the UWCCC as well as the wider non-UW research community in-line with the development and clinical translation of biomarkers from the circulation that can predict or detect therapeutic resistance in patients with solid tumor diseases. Circulating biomarkers are evaluated on clinical specimens, primarily patient blood draws, through a series of sample processing steps, including ficoll density centrifugation, magnetic depletion of normal blood cells using standard MACS columns, magnetic enrichment and protein staining or nucleic acid (DNA/mRNA) extraction of metastatic tumor cells using either a customized pipetting robot or a handheld microfluidic device. Analytical systems include fluorescence microscopy image acquisition, raw image conversion into quantitative data using both automated image processing algorithms and manual review of identified objects. Characterization of mRNA is achieved with reverse-transcription quantitative PCR (RT-qPCR). With the ultimate goal of implementing these circulating biomarker diagnostics into clinical practice, the CBC is also actively developing the controls and analytical validation datasets required for regulatory approval.

Our team of highly cooperative researchers coordinate the receipt, processing and analysis of 10-20 patient samples each week, testing a number of different protein and nucleic acid biomarkers, for numerous different projects involving basic research and clinical trials.

Responsibilities:

Designs methodology, conducts data collection and analysis, and prepares reports for client-based research.

• 20% Assists with the development of research methodologies and procedures according to client-based objectives and specifications
• 20% Identifies concerns and recommends solutions to leadership
• 30% Collects and analyzes basic research data, conducts experiments and interviews, and documents results according to established policies and procedures
• 5% Prepares reports and materials and disseminates information to appropriate entities
• 10% Reviews and edits research protocols under general supervision
• 15% Trains individuals and groups on equipment operations, research protocols, and techniques within a specialized laboratory or research area

Institutional Statement on Diversity:

Diversity is a source of strength, creativity, and innovation for UW-Madison. We value the contributions of each person and respect the profound ways their identity, culture, background, experience, status, abilities, and opinion enrich the university community. We commit ourselves to the pursuit of excellence in teaching, research, outreach, and diversity as inextricably linked goals.

The University of Wisconsin-Madison fulfills its public mission by creating a welcoming and inclusive community for people from every background – people who as students, faculty, and staff serve Wisconsin and the world.

Education:

Preferred
Bachelor’s Degree
Preferably in Molecular Biology, Biochemistry, or other closely related biological science

Qualifications:

• Previous experience in molecular biology methods, next generation sequencing, and immunology is desired but not required.
• Experience with microfluidic technologies and fluorescence microscopy, as well as a circulating tumor cell research background is desired but not required.
• Previous experience in flow cytometry is desired but not required.

Work Type:

Full Time: 100%

It is anticipated this position requires work be performed in-person, onsite, at a designated campus work location.

Appointment Type, Duration:

Ongoing/Renewable

Salary:

Minimum $43,071 ANNUAL (12 months)
Depending on Qualifications

Additional Information:

• Work experience should demonstrate dependability, flexibility, and maturity. Candidates must be effective at building interpersonal relationships with constructive interactions, be clear and effective communicators, promote and create collegial environments that value accountability. Employees will also be expected to uphold UWCCC core values as defined below:
• Diversity & Inclusiveness: Embrace differences and promote fairness and equity while fostering a sense of belonging.

– Respect: Demonstrate respect for self and others – behave professionally.

• Integrity: Act with integrity and honesty.
• Teamwork: Commit to and demonstrate teamwork.
• Excellence: Ensure excellence, quality, and high ethical standards in conduct and performance.

The School of Medicine and Public Health will not sponsor work visas for this position, thus, in compliance with federal law, all persons hired will be required to verify eligibility to work in the United States by completing the required I-9 form upon hire.

How to Apply:

To apply for this position, please click on the “Apply Now” button. You will be asked to upload a resume and cover letter as a part of the application process. Please ensure that the resume and cover letter address how you meet the minimum/preferred qualifications for the position. You may also be asked to provide three professional/supervisor references during the recruitment process. References will not be contacted prior to notifying you.

Contact:

Devonne Tucker
[email protected]
608-263-9404
Relay Access (WTRS): 7-1-1. See RELAY_SERVICE for further information.

Official Title:

Client-Based Researcher I(RE001)

Department(s):

A53-MEDICAL SCHOOL/CARBONE CANC CTR/CANC CTR

Employment Class:

Academic Staff-Renewable

Job Number:

302566-AS

The University of Wisconsin-Madison is an Equal Opportunity and Affirmative Action Employer.

Qualified applicants will receive consideration for employment without regard to, including but not limited to, race, color, religion, sex, sexual orientation, gender identity, national origin, age, pregnancy, disability, or status as a protected veteran and other bases as defined by federal regulations and UW System policies. We promote excellence through diversity and encourage all qualified individuals to apply.

Employment may require a criminal background check. It may also require you and your references to answer questions regarding sexual violence and sexual harassment.

The University of Wisconsin System will not reveal the identities of applicants who request confidentiality in writing, except that the identity of the successful candidate will be released. See Wis. Stat. sec. 19.36(7).

The Annual Security and Fire Safety Report contains current campus safety and disciplinary policies, crime statistics for the previous 3 calendar years, and on-campus student housing fire safety policies and fire statistics for the previous 3 calendar years. UW-Madison will provide a paper copy upon request; please contact the University of Wisconsin Police Department.